Topical Seminar: Tomislav Stankovski (Lancaster, UK)

From Thursday 28th June 2018 at 14:00
To Thursday 28th June 2018 at 15:30

Location : INS seminar room Hopital La timone (5th floor, red wing) Marseille

"Coupling functions in neuroscience"

Faculty of Medicine, Ss Cyril and Methodius University, Skopje 1000, Macedonia
Department of Physics, Lancaster University, Lancaster LA1 4YB, United Kingdom

Interacting dynamical systems abound in nature and often the interest is not only to understand if, but also how they interact i.e. to reveal the functions and mechanisms that define and connect them. Coupling functions contain detailed information about the functional mechanisms underlying the interactions and prescribe the physical rule specifying how an interaction occurs [1]. Using a method based on dynamical Bayesian inference [2], we show how one can reconstruct and assess the coupling functions from phase dynamics of oscillatory data. Then, we present number of recent applications in neuroscience – including the neural cross-frequency coupling functions in eyes open/eyes closed resting state [3], and the state of general anaesthesia with two anaesthetics (propofol and sevoflurane) [4]; as we also present bursting neuronal coupling functions from
multielectrode array (MEA) recordings of interacting neurons from rats.

References:
[1] Stankovski et al., Rev. Mod. Phys., (2017)
[2] Stankovski et al., Phys. Rev. Lett. (2012)
[3] Stankovski et al., Front. Syst. Neurosci. (2017)
[4] Stankovski et al., Philos. Trans. Royal Soc. A (2016)

For any question, feel free to contact:
Benjamin Morillon (bnmorillon@gmail.com) or Adam Williamson (adam.WILLIAMSON@univ-amu.fr)

 

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Keynote Seminar: Mary Pat McAndrews (Toronto, Canada)

From Thursday 7th June 2018 at 14:00
To Thursday 7th June 2018 at 15:30

Location : INS new seminar room on 5th floor Faculty of medecine, La timone Marseille

"What are best practices in using fMRI to assess cognitive integrity and predict post-operative morbidity in temporal lobe epilepsy ?"

The use of fMRI to understand how cognitive processes such as language and memory are disrupted by neurological disorders is starting to bear fruit in clinical care. In the case of temporal-lobe epilepsy, the focus is identifying imaging features that will assist with diagnosis and prognosis in the service of surgical planning. While much of the early translational work was concerned with focal task-related activation, it is becoming clear that network properties and connectivity amongst brain regions may be a more sensitive and appropriate biomarker of functional integrity of brain networks that support complex cognitive operations, and that predicting the impact of focal damage or surgery requires an appreciation of those networks. Against this background, I will discuss analyses of resting state functional MRI (rsfMRI) as an emerging technique to address clinically-relevant questions about memory and language in the context of medial temporal lobe epilepsy.

For any question, feel free to contact:
Benjamin Morillon (bnmorillon@gmail.com) or Adam Williamson (adam.WILLIAMSON@univ-amu.fr)

 

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Keynote Seminar: Kristina Malmgren (Göteborg)

From Thursday 3rd May 2018 at 14:00
To Thursday 3rd May 2018 at 15:30

Location : INS temporary seminar room (5th floor) Faculty of medecine, La timone Marseille

"What do we know about the comprehensive long-term outcomes of epilepsy surgery – the Swedish contribution"

Epilepsy surgery is a recognized option in the management of adults and children with drug-resistant epilepsy. Advances in investigational techniques have widened the spectrum of surgical candidates. In the short term, rates of seizure freedom are relatively high, but seizure recurrence can still occur in the long term. There are methodological hurdles to overcome when assessing longer-term seizure outcomes. Patients and parents have hopes for improvements that are not limited to seizure control but pertain to many other areas of life - e g cognition, neurodevelopment, academic and vocational outcomes, and quality of life – which are of importance when determining whether a treatment is beneficial. In a number of these areas longer-term data are scarce or missing. Most patients are young when operated and they need counseling about the long-term perspective in order to make an informed decision about surgery. The Swedish National Epilepsy Surgery Register has prospectively included all patients in Sweden who have undergone epilepsy surgery since 1990. Hence the register is population based in a setting where this specialized treatment is public health care financed, which renders the data more generalisable than single center follow-ups. We have structured follow-ups up to 20 years after surgery encompassing information on seizures, antiepileptic drug treatment, work, and driving. We also pursue long-term cognitive follow-up studies of patients after temporal lobe resection; survey studies and qualitative interview studies in specified national patient/parent cohorts identified through the register. Results from these outcome studies will be presented concerning long-term seizure outcome, antiepileptic drug treatment outcome, vocational outcome, cognitive outcome and quality of life. From the interview studies data on patients’ expectations and experiences of epilepsy surgery will be presented. This knowledge is important in the counseling process, in order for patients to have realistic expectations on what they can gain from epilepsy surgery.

For any question, feel free to contact:
Benjamin Morillon (bnmorillon@gmail.com) or Adam Williamson (adam.WILLIAMSON@univ-amu.fr)

 

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Keynote Seminar: F-Xavier Alario (Marseille)

From Thursday 12th April 2018 at 14:00
To Thursday 12th April 2018 at 15:30

Location : INS temporary seminar room (5th floor) Faculty of medecine, La timone Marseille

"Neuro-physiological evaluation of psycho-linguistic hypothesis: A personal account"

Psycholinguistic models describe the cognitive processes that allow speakers to produce and comprehend language. These language processes are undoubtedly generated by neuro-physiological activities. Yet, despite the available evidence, much work remains to be done to understand the functions that link cognition and neuro-physiology, particularly in what concerns the ability to produce language. In recent years, we have used intra-cerebral neuro-physiological data to test cognitive hypothesis about language production. In the talk, I will discuss a few difficulties we have faced and how we have addressed them in our investigation of word selection processes. References: 1.Dubarry, A.-S., Llorens, A., Trébuchon, A., Carron, R., Liégeois-Chauvel, C., Bénar, C.*, & Alario, F.-X.* Estimating Parallel Processing in a Language Task Using Single-Trial Intracerebral Electroencephalography. Psychol. Sci. 28, 414–426 (2017). 2.Llorens, A. Dubarry, A.-S., Trébuchon, A., Chauvel, P., Alario, F.-X., & Liégeois-Chauvel, C. Contextual modulation of hippocampal activity during picture naming. Brain Lang. 159, (2016).

For any question, feel free to contact:
Benjamin Morillon (bnmorillon@gmail.com) or Adam Williamson (adam.WILLIAMSON@univ-amu.fr)

 

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Keynote Seminar: Fabrice Wendling (Rennes)

From Thursday 5th April 2018 at 14:00
To Thursday 5th April 2018 at 15:30

Location : INS seminar room (5th floor) Faculty of medecine, La timone Marseille

"Neurostimulation for diagnosis and therapy in epilepsy: from “in silico” models to “in vivo” applications"

Diagnosis. Neurostimulations can be used to probe neuronal circuits. Using a computational modeling approach in combination with in vivo and in vitro electrophysiological recordings, we showed that extracellular local bipolar stimulation at low intensity allows preferential activation of GABAergic interneurons. From this procedure, we devised a quantitative index that reflects the excitability of locally-stimulated neuronal networks (the neuronal network excitability index or NNEI). The NNEI is computed from stimulation-induced responses recorded as extracellular signals (Local Field Potentials, LFPs) evoked with optimally-tuned intensity and frequency parameters. The proposed probing method can be used to identify hyperexcitable brain regions in patients with focal epilepsy.

Therapy. We study the effects of local direct current stimulation (LDCS) effects on hyperexcitable tissue, by i) analyzing the impact of electrical currents locally applied on epileptogenic brain regions, and ii) characterizing currents achieving an “anti-epileptic” effect (excitability reduction). First, a neural mass model of hippocampal circuits was extended to accurately reproduce the features of hippocampal paroxysmal discharges (HPDs) observed in a mouse model of epilepsy. Second, model predictions regarding current intensity and stimulation polarity were confronted to in vivo mice recordings during LDCS. Simulations showed that significant decrease of simulated HPDs (in duration and occurrence rate, not in amplitude) could be obtained for specific configurations (electrode position, polarity, intensity). Predictions were successfully verified experimentally in epileptic mice. Results provide support for further model-guided design of neuromodulation therapy.

For any question, feel free to contact:
Benjamin Morillon (bnmorillon@gmail.com) or Adam Williamson (adam.WILLIAMSON@univ-amu.fr)

 

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Topical Seminar: Véronique Boulenger (Lyon)

From Thursday 29th March 2018 at 14:00
To Thursday 29th March 2018 at 15:30

Location : INS temporary seminar room (5th floor) Faculty of medecine, La timone Marseille

"Brain oscillations during natural speech perception: the case of speech rate variations"

Oscillation-based models of speech perception suggest a close correspondence between speech rhythm and cortical oscillations: neural oscillations would synchronize to the quasi-regular temporal cues in speech across multiple timescales, therefore facilitating the partitioning of the acoustic stream into relevant linguistic units crucial for language comprehension (Ghitza, 2011; Giraud & Poeppel, 2012; Peelle & Davis, 2012; Poeppel, 2003). EEG/MEG studies have convincingly demonstrated coupling between auditory cortical oscillations and slow modulations in the temporal envelope of speech in the theta band (e.g., Ahissar et al., 2001; Gross et al., 2013; Luo & Poeppel, 2007; Peelle et al., 2013), namely in a frequency range which coincides with the average syllabic rate of speakers across languages (Pellegrino et al., 2011). Here I will present some MEG data in adults as well as in typically-developing children (8-13 years old) showing changes in the properties of cortico-acoustic coupling when natural speech perception shifts from normal to fast syllabic rate (with natural or artificial acceleration). Source-level coherence analyses indeed revealed entrainment of neuronal oscillations that followed the changes in speech envelope (though in adults only) as well as in fundamental frequency (both in adults and children) with increasing speech rate. Children data furthermore showed alignment of theta oscillatory activity in left (pre)motor regions when speech was naturally accelerated. I will discuss these findings in light of multi-time resolution models of speech perception as well as the role of the motor system in speech perception.

For any question, feel free to contact:
Benjamin Morillon (bnmorillon@gmail.com) or Adam Williamson (adam.WILLIAMSON@univ-amu.fr)

 

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Keynote Seminar: Jean-Luc Schwartz (Grenoble)

From Thursday 15th March 2018 at 14:00
To Thursday 15th March 2018 at 15:30

Location : INS seminar room (5th floor) Faculty of medecine, La timone Marseille

"COSMO, a Bayesian model of perceptuo-motor interactions in speech communication"

I will present COSMO (Communicating Objects using Sensory-Motor Operations), a computational model enabling to analyze the functional role of sensory-motor interactions in speech perception and in speech production. I will present three properties of COSMO in speech perception, respectively called redundancy, complementarity (with the “auditory-narrowband versus motor-wideband” framework) and “specificity” (according to which auditory cues would be more efficient for vowel decoding and motor cues more efficient for plosive articulation decoding). I will sketch a possible neuroanatomical architecture for COSMO, and capitalize on properties of the auditory vs. motor decoders to address various neurocognitive studies of the literature. I will conclude on the interest of combining a complementary exogenous decoding system, optimally fitted on the environment stimuli, with an endogenous decoding system, equipped with generative properties.

For any question, feel free to contact:
Benjamin Morillon (bnmorillon@gmail.com) or Adam Williamson (adam.WILLIAMSON@univ-amu.fr)

 

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Topical Seminar: Valérie Crepel (Marseille)

From Thursday 22nd February 2018 at 14:00
To Thursday 22nd February 2018 at 15:30

Location : INS seminar room (5th floor) Faculty of medecine, La timone Marseille

"Synaptopathy in Epilepsy: causes and consequences"

In both human patients and animal models of TLE, neuronal tissue undergoes major reorganization; some neurons die while others sprout and form novel aberrant connections (Tauck and Nadler, 1985, Represa et al. 1987, Nadler, 2003; Gabriel et al., 2004; Dudek & Sutula, 2007). This phenomenon is best documented in the dentate gyrus where mossy fiber (MF) axons sprout to form aberrant glutamatergic excitatory synapses onto other dentate granule cells (DGCs) leading to the formation of functional recurrent excitatory circuits. This accounts for, in part, the enhanced ability of the hippocampus to generate epileptiform activity. MF sprouting also induces a reorganization of KAR-mediated synaptic transmission, with a shift in the nature of glutamatergic transmission in DGCs (Epsztein et al. 2005, Epsztein et al. 2010, Artinian et al. 2011, Peret et al. 2014; Artinian et al. 2015; Matsuda et al. 2016). Our data reveal that ectopic kainate receptors drastically impact the computational properties of DGCs and play a major role in epileptiform activities.

For any question, feel free to contact:
Benjamin Morillon (bnmorillon@gmail.com) or Adam Williamson (adam.WILLIAMSON@univ-amu.fr)

 

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(Français) Matinée d’information et d’échanges sur l’épilepsie 2018

From Saturday 17th February 2018
To Saturday 17th February 2018

Location : l’Hôpital de la Timone Marseille

Nous sommes très heureux de vous inviter à participer à notre prochaine matinée d'information et d’échanges sur l’épilepsie prévue le 17/02/2018 à l’Hôpital de la Timone organisée par le service de Neurophysiologie du Prof. Bartolomei, le projet Epinov, et Epilepsie France.

Inscription gratuite mais obligatoire avant le 1 février sur le site suivant: http://bit.ly/2lWt4tk

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INS/INT Keynote Seminar – Danielle Bassett (Philadelphia, USA)

From Friday 26th January 2018 at 14:30
To Friday 26th January 2018 at 16:00

Location : INS seminar room (5th floor) Faculty of medecine, La timone Marseille

"The Network Architecture of Human Thought"

Human thought is predicated on a complex architecture of interconnections that enable information transmission between distinct areas ofthe brain. Yet gaining a fundamental understanding of this architecture has remained challenging, largely due to insufficiencies in traditional imaging techniques and analytical tools. In concerted efforts to address these challenges, neuroscientists have begun to combine recent breakthroughs in non-invasive brain imaging techniques with the conceptual notions and mathematical tools of network science – leading to the emerging field ofnetwork neuroscience. This talk will highlight early successes in this field leading to fundamental understanding of healthy human thought, its development over childhood, and its alteration in psychiatric disease and neurological disorders. The talk will close by commenting on current frontiers and future potential in health care, business, and education sectors.

For any question, feel free to contact:
Benjamin Morillon (bnmorillon@gmail.com) or Adam Williamson (adam.WILLIAMSON@univ-amu.fr)

 

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INS Topical Seminar – Davide Ragozzino (Rome, Italy)

From Thursday 30th November 2017 at 14:00
To Thursday 30th November 2017 at 15:30

Location : INS seminar room (5th floor) Faculty of medecine, La timone Marseille

"Microglia shape presynaptic properties at developing glutamatergic synapses"

Deficient neuron-microglia signaling during brain development is associated with abnormal synaptic maturation. However, the precise impact of deficient microglia function on synaptic maturation and the mechanisms involved remain poorly defined.
Here we report that mice defective in neuron-to-microglia signaling via the fractalkine receptor (Cx3cr1 KO) show reduced microglial branching and altered motility and develop widespread deficits in glutamatergic neurotransmission. We characterized the functional properties of CA3-CA1 synapses in hippocampal slices from these mice and found that they display altered glutamatergic release probability, maintaining immature properties also at late developmental stages. In particular, CA1 synapses of Cx3cr1 KO show: (i) immature AMPA/NMDA ratio across developmental time displaying a normal NMDA component and a defective AMPA component of EPSC; (ii) defective functional connectivity, as demonstrated by reduced current amplitudes in the input/output curve; and (iii) greater facilitation in the paired pulse ratio (PPR), suggesting decreased release probability. In addition, minimal stimulation experiment revealed that excitatory synapses have normal potency, but an increased number of failures, confirming a deficit in presynaptic release. When the deficit in release probability was corrected by performing experiments in high Ca2+/Mg2+, excitatory synapses showed normal synaptic multiplicity and AMPA/NMDA ratio.
These results establish that neuron-microglia interactions profoundly influence the functional maturation of excitatory presynaptic synapse function.

For any question, feel free to contact:
Benjamin Morillon (bnmorillon@gmail.com) or Adam Williamson (adam.WILLIAMSON@univ-amu.fr)

 

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INS Keynote Seminar – Lyon Research Team (France)

From Tuesday 28th November 2017 at 14:00
To Tuesday 28th November 2017 at 15:30

Location : INS seminar room (5th floor) Faculty of medecine, La timone Marseille

"Dynamics of Embodied Cognition in Humans and Robots"

Jocelyne Ventre-Dominey, Carol Madden-Lombardi and Peter Dominey

Human and Robot Cognitive Systems- Inserm U1208- Bron, France

The goal of our research is to understand the neural basis and organization of the sensori-motor systems responsible for visuo-spatial orientation and spatial representation in interaction with language. Over the past few decades, embodied cognition theory has suggested a tight coupling between sensori-motor functions and language, as understanding verbal stimuli (words, sentences, narrative) triggers sensori-motor experiential traces grounded in neural networks. Beyond language, the comprehension of perceived events in the world around us relies on the internal simulation of our own previous experiences in a multimodal framework. Such an embodied theory of meaning implies interacting cognitive systems including tight coupling between visuo-spatial representations and language functions. While these two functions have been well studied in separate fields, the mechanisms and neural substrates of their coupling in higher-order cognitive operations remain to be characterized.

By combining neuroscience and psychology expertise in both sensori-motor and language domains, integrated with computational neuroscience and neuro-robotics, our team project addresses several themes of this general topic: 1) the neural mechanisms and the organization underlying sensori-motor interactions involved in both space representation and language comprehension, 2) the organization of the spatio-temporal structure of embodied event simulations serving narrative comprehension and 3) the development of neuro-computational models of these dynamic cognitive functions for model-based analysis of brain dynamics, and for developing cognitive functions in humanoid robots. Finally these research findings will provide a basis for further translational applications of these cognitive functions in aging, reeducation, and psychiatry (autism).

For any question, feel free to contact:
Benjamin Morillon (bnmorillon@gmail.com) or Adam Williamson (adam.WILLIAMSON@univ-amu.fr)

 

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INS/INT Keynote Seminar – Stefano Panzeri (Rovereto, Italy)

From Thursday 9th November 2017 at 14:00
To Thursday 9th November 2017 at 15:30

Location : INS seminar room (5th floor) Faculty of medecine, La timone Marseille

"The relationship between cross-cell coupling and the timescales of population coding across cortex"

The cortex needs to represents information across a wide range of timescales, from the millisecond-scale required to encode rapidly fluctuating sensory stimuli, to the maintenance of information over seconds that is required to implement certain behavioral choices. Do such diverse timescales result mostly from features intrinsic to individual neurons or from correlated activity in neuronal populations ? Here we report that population codes can be essential to achieve long coding timescales, and that the properties and time scales of population codes differ between sensory and association cortices. We compared coding for sensory stimuli and behavioral choices in auditory cortex (AC) and posterior parietal cortex (PPC) as mice performed a sound-localization task. Auditory stimulus information was strong in AC but weak in PPC, and both regions contained choice information. Although AC and PPC coded information by tiling in time neurons that were transiently informative, the areas had major differences in functional coupling between neurons, measured as activity correlations that could not be explained by task events. Coupling among PPC neurons was strong and extended over long time lags, whereas coupling among AC neurons was weak and short-lived. Stronger coupling in PPC led to a population code with long timescales and a representation of choice that remained consistent for approximately one second. In contrast, AC had a code with rapid fluctuations in stimulus and choice information over hundreds of milliseconds. Our results reveal that population codes differ across cortex and that cross-cell coupling affects the timescale of information coding.
This is joint work with Carolyne Runyan at Chris Harvey at Harvard Medical School and with Eugenio Piasini at IIT.

For any question, feel free to contact:
Benjamin Morillon (bnmorillon@gmail.com) or Adam Williamson (adam.WILLIAMSON@univ-amu.fr)

 

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INS Topical Seminar – Beate Diehl (London, UK)

From Thursday 2nd November 2017 at 16:00
To Thursday 2nd November 2017 at 18:00

Location : INS seminar room (5th floor) Faculty of medecine, La timone Marseille

 

"Direct Electrical Cortical Stimulation: Disrupting the epileptic brain - What can we learn about brain function"

Direct Electrical Cortical Stimulation is used to map cortical functions during awake surgery and chronic intracranial EEG (iEEG) recordings for presurgical evaluation in epilepsy. Although there is lack of standardization across centers, it is considered the gold standard to for mapping of cortical function and to define eloquent cortex. It allows a unique opportunity to gain access to the epileptic brain. In this talk I will show cortical stimulation mapping using grids mainly, illustrating effects and side effects of stimulation mapping and opportunities to define brain function also in less accessible regions such as the medial frontal lobe.

For any question, feel free to contact:
Benjamin Morillon (bnmorillon@gmail.com) or Adam Williamson (adam.WILLIAMSON@univ-amu.fr)

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INS Topical Seminar – Andrea Protzner (Calgary, Canada)

From Thursday 12th October 2017 at 16:00
To Thursday 12th October 2017 at 18:00

Location : INS seminar room (5th floor) Faculty of medecine, La timone Marseille

 

"How do age-related changes in brain signal variability relate to individual differences in functional capacity and performance?"

Recent empirical work has demonstrated that variability in network dynamics differs between younger and older adults. With increasing age, brain signal variability decreases at coarse temporal scales and increases at fine temporal scales, suggesting a shift from global toward more local neural processing. I will discuss how these age-related changes relate to task performance (e.g., visual word recognition in healthy adults), and how they relate to the capacity for normalization in brain disease (e.g., depression).

For any question, feel free to contact:
Benjamin Morillon (bnmorillon@gmail.com) or Adam Williamson (adam.WILLIAMSON@univ-amu.fr)

 

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(Français) 20èmes journées Françaises de l’Epilepsie (JFE)

From Monday 9th October 2017 at 11:00
To Thursday 12th October 2017 at 16:00

Location : Palais du Pharo 58, Boulevard Charles Livon Marseille

 

JFE

 

 

This page is only available in French

 

 

 

 

 

 

Enregistrer



INS Topical Seminar – David Howard (Newcastle, UK)

From Thursday 5th October 2017 at 16:00
To Thursday 5th October 2017 at 18:00

Location : INS seminar room (5th floor) Faculty of medecine, La timone Marseille

 

"Treatment of word retrieval: contrasting results from 2 RCTs"

This talk will describe the results of two partly parallel randomised controlled crossover treatment trials. Both contrasted a treatment emphasising semantics with a treatment concentrating on phonological information. One trial was with people with stroke aphasia and the second with normal children with word finding difficulties. Both trials found improvement only with treated items, but they differed in whether the results could be predicted from the background tests probing related cognitive functions.

For any question, feel free to contact:
Benjamin Morillon (bnmorillon@gmail.com) or Adam Williamson (adam.WILLIAMSON@univ-amu.fr)

 

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INS Topical Seminar – Jean-Rémi King (New York)

From Monday 28th August 2017 at 10:30
To Monday 28th August 2017 at 12:00

Location : INS new seminar room on 5th floor Faculty of medecine, La timone Marseille

 

"Identifying the neural architecture of human cognition"

What computations are specific to human cognition? Are they supported by a particular neural architecture? How might such an architecture supplement the design of machine learning algorithms? Here, I will argue that the recent developments in 1) machine learning and 2) temporally-resolved neuroimaging offer a new opportunity to address these foundational issues. In particular, I will show how we can track the unfolding of complex cognitive processes, such as perceptual decision making and speech comprehension, and identify what representations the human brain encodes, selects, and maintains at each instant in time. The present studies show how we can isolate and track a multitude of processing stages reminiscent of deep neural networks. Finally, I outline a few promising research directions to investigate parallel, serial, and recursive computations in syntactic processing and conceptual composition. I argue that the present research program will pave the way to integrate the disciplines of biological and artificial cognition.

For any question, feel free to contact:
Demian Battaglia (demian.battaglia@univ-amu.fr) or Benjamin Morillon (bnmorillon@gmail.com)

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INS Topical Seminar – Christine Métin (Paris)

From Thursday 13th July 2017 at 14:00
To Thursday 13th July 2017 at 15:30

Location : INS new seminar room on 5th floor Faculty of medecine, La timone Marseille

"Cellular mechanisms regulating the cortical distribution of GABAergic interneurons"

The p21 activated kinases (PAKs) are activated by Rac1 and Cdc42 and regulate the dynamics and contractility of the acto-myosin cytoskeleton, and the turnover of adhesive contacts. Mutations in one isoform, PAK3, are responsible in humans of X-linked non-syndromic intellectual disability. Pak3 is expressed in tangentially migrating interneurons in the developing cortex. By overexpressing mutants that mimic human mutations (kinase dead or defective for GTPase binding) or a constitutively active mutant, we have analyzed the influence of PAK3 activity on the morphology, dynamic behavior and on the trajectories of migrating interneurons in the developing cortex.

Christine Métin, DR2 INSERM, co-leads with P. Gaspar the team ”Developmental mechanisms of brain disorders” at Institut du Fer à Moulin (IFM) in Paris. With her group, C. Métin analyzes the cellular mechanisms that regulate the long distance migration of cortical interneurons from the basal forebrain to the developing cortex. She uses in vivo models to study how the migratory defects of interneurons alter their final distribution in the cortical target. In collaboration with the team of C. Bernard, she studies the consequences of interneuron migratory defects on the activity of cortical networks.

For any question, feel free to contact:
Demian Battaglia (demian.battaglia@univ-amu.fr) or Benjamin Morillon (bnmorillon@gmail.com)



1st AM*IDEX CompNeuro Days

From Wednesday 12th July 2017 at 9:00
To Thursday 13th July 2017 at 17:00

Location : INMED, Luminy

 
The aim of this workshop is to gather researchers active in the field of general computational neuroscience to illustrate the diversity of its approaches and the richness of cooperation between theorists and experimentalists
and all this in an informal atmosphere favourable to discussions. 

PhD students are warmly welcome and will be given the opportunity to present their research (not necessarily computational, on the contrary!) in Blitz oral presentations (ca. 5 min) and/or poster.

*** The registration is open and compulsory (deadline July 2nd), but free ***

In addition the students willing to present their result should send an email with a short title and abstract, name of the supervisor to the organisers:
Alessandro Torcini (torcini@gmail.com), David Angulo Garcia (david.angulo-garcia@univ-amu.fr), Demian Battaglia (demian.battaglia@univ-amu.fr)

They will then be informed of the type of presentation assigned to them (Blitz oral or poster). There are only limited slots available for oral, so priority will be given to thematic diversity.

List of speakers:
• Nicolas Brunel (Chicago, USA),
• Frederic Chavane (Marseille, France)
• Daniel Durstewitz ( Mannheim, Germany)
• Boris Gutkin (Paris, France)
• Vincent Hakim (Paris, France)
• David Hansel (Paris, France)
• Viktor Jirsa (Marseille, France)
• Anna Levina (Klosterneuburg, Austria)
• Nicolas Mallet (Bordeaux, France)
• Arnaud Malvache (Marseille, France)
• Gianluigi Mongillo (Paris, France)
• Alfonso Renart (Lisbon, Portugal)
• Petra Ritter (Berlin, Germay)


Sponsors:

A*Midex, INMED, Institut de Neurosciences des Systèmes, Institut de Neurosciences de La Timone, EPINEXT, PhD Program in Integrative and Clinical Neurosciences, Mediterranean Neuroscience Society, Marie Curie Actions, Società Italiana Caos e Complessità