PhysioNet Team Leader

Christophe Bernard

Christophe Bernard, DR Inserm
PhysioNet Team Leader



Phone number:
+33 4 91 29 98 06


1984    Ecole Centrale Paris (Mathematics and theoretical physics)
1990    Ph.D in Neuroscience: Theoretical and experimental study of the immature cerebellar cortex. University of Paris VI

1989        Permanent position INSERM
1991-1994    Post-Doctoral, Southampton University, UK
1995-1999    INSERM U29, Paris, France
1999-2001    Sabbatical leave, Baylor College of Medicine, Houston, TX
2001-2004    INSERM U29, Luminy, Marseille, France
2004-2012    INSERM U751, Timone, Marseille, France
2012-              INSERM U1106, Timone, Marseille, France

Advisory functions
-    Since 2009    Scientific advisor of Laboratory of Microelectronics (Gardanne, France)
-    Since 2005    Treasurer and ad hoc member of Neurobiology Commission of ILAE (International League Against Epilepsy)
-    Since 2002    Member of Scientific council of FFRE (Fédération Française pour la Recherche sur l’Epilepsie – French Epilepsy Research Foundation)
-    2009-2010    Scientific Delegate (DS for LS5) for AERES (French Agency for the scientific evaluation of research laboratories)
-    2006-2010    Member of Program Committee of SfN (Society for Neuroscience) – Chair of Theme C (Neurological Disorders)
-    1998-2002    ad hoc member, INSERM Neuroscience survey committee.

Since 2011, reviewing editor for The Journal of Neuroscience





1.    “Hub GABA neurons mediate high frequency oscillations at ictal-like onset in the immature hippocampus” Quilichini P, Le Van Quyen M, Ivanov A, Turner D, Carabalona A, Esclapez M, Bernard C. Neuron 2012 (in press).

2.    “Changes in interictal spike features precede the onset of temporal lobe epilepsy” Chauvière M, Doubelt T, Ghestem A, Siyoucef S, Wending F, Huys R, Jirsa V, Bartolomei, F., Bernard, C. Annals of Neurology, 2012 (in press).

3.    “Dorsal-ventral differences in intrinsic properties in developing CA1 pyramidal cells” Marcelin M, Liu Z, Chen Y, Lewis AS, Becker A, McClelland S, Chetkovich DM, Migliore M, Baram TZ, Esclapez M, Bernard C. J Neuroscience, 2012 (in press)

4.    “Neuron-restrictive silencer factor-mediated hyperpolarization-activated cyclic nucleotide gated channelopathy in experimental temporal lobe epilepsy.” McClelland S, Flynn C, Dubé C, Richichi C, Zha Q, Ghestem A, Esclapez M, Bernard C*, Baram TZ. Annals of Neurology, Sep;70(3):454-64,2011. *Corresponding author.

5.    “Early and persistent cognitive deficits and alterations in network activity during epileptogenesis in Temporal Lobe Epilepsy” Chauvière M, Thinus-Blanc C, Bartolomei F, Esclapez M, Bernard C. J Neuroscience, 29, 5402-10, 2009.

6.    “Interneuron diversity series - Multiple facets of GABAergic neurons and synapses: multiple fates of GABA signalling in epilepsies” Cossart R, Bernard C, Ben-Ari Y. Trends in Neuroscience. 28, 108-115, 2005.

7.    “Altering cannabinoid signaling during development disrupts neuronal activity” Bernard C*, Milh M, Morozov T, Ben-Ari Y, Freund F, Gozlan H. PNAS. 102, 1388-1393, 2005. * CA

8.    “Acquired dendritic channelopathy in epilepsy” Bernard C*, Anderson A, Poolos N, Becker A, Beck H, Johnson D. Science. 305, 532-535, 2004. *CA

9.    “GABAergic inhibition in temporal lobe epilepsy: more in somata, less in dendrites” Cossart R, Dinoncourt C, Hirsch J.C, Ben-Ari Y, Esclapez M, Bernard C. Nature Neuroscience. 4, 52-62, 2001.

10.  “Presynaptic kainate receptors that enhance quantal release of GABA on CA1 hippocampal interneurons” Cossart R, Esclapez M, Tyzio R, Dinoncourt C, Hirsch J.C, Ben-Ari Y, Bernard C. Neuron 29, 497-508, 2001.