Job Offers | Post-doc in Neuroscience

Posted by on Aug 07, 2017 in Job offer | Comments Off

Post-doc in Neuroscience

PhysioNet Team, Institute of System Neuroscience (INS), UMR1106 AMU-Inserm, Marseille, FRANCE

One postdoc position (at least one year) is offered at INS in the Physionet team in the field of Alzheimer, starting end of 2017 – beginning of 2018.

Caffeine exposure in utero as a risk factor for the development of Alzheimer’s disease

We have previously shown that in utero caffeine exposure through the dam (equivalent of 2-3 espressos in humans) delays the insertion of some GABA neuron populations in the hippocampus and
cortex, with deleterious consequences (enhanced sensitivity to epilepsy and cognitive deficits) in offspring (Silva et al., Science Trans Med, 2013; Fazeli et al., Exp Neurol, 2017). Building on this we wish to determine whether caffeine exposure in utero speeds up Alzheimer’s disease in a genetic KI mouse model. To address this issue, we will combine in vivo and in vitro electrophysiology, functional morphology and behavioral studies.
Prior experience in in vitro patch clamp electrophysiology is required. Experience in functional morphology is a plus. Candidates should apply by sending a CV, a brief outline of current research, scientific interests and career goals, as well as the name and contact details of at least two academic references to Dr. Christophe Bernard (christophe.bernard@univ-amu.fr).

More information about the the PhysioNet Group can be found HERE